Reproducibility of behavioral phenotypes in mouse models - a short history with critical and practical notes
Author(s) / Creator(s)
Voikar, Vootele
Other kind(s) of contributor
University of Helsinki
Abstract / Description
Progress in pre-clinical research is built on reproducible findings, yet reproducibility has different dimensions and even meanings. Indeed, the terms reproducibility, repeatability, and replicability are often used interchangeably, although each has a distinct definition. Moreover, reproducibility can be discussed at the level of methods, analysis, results, or conclusions. Despite these differences in definitions and dimensions, the main aim for an individual research group is the ability to develop new studies and hypotheses based on firm and reliable findings from previous experiments. In practice this wish is often difficult to accomplish. In this review, issues affecting reproducibility in the field of mouse behavioral phenotyping are discussed.
Keyword(s)
behavioral phenotyping mouse reproducibility core facilityPersistent Identifier
Date of first publication
2020-08-13
Journal title
Journal for Reproducibility in Neuroscience
Volume
1
Article number
1375
Publisher
PsychArchives
Publication status
publishedVersion
Review status
notReviewed
Is version of
Citation
Voikar, V. (2020). Reproducibility of behavioral phenotypes in mouse models - a short history with critical and practical notes. Journal for Reproducibility in Neuroscience, 1, 1375. https://doi.org/10.31885/jrn.1.2020.1375
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jrn.1.2020.1375.pdfAdobe PDF - 234.53KBMD5: ece84f2e257203a0cdbe61b6fa2fbe88Description: Version of RecordRationale for choice of sharing level: Papers published in the Journal for Reproducibility in Neuroscience are CC BY-SA (https://journals.helsinki.fi/jrn/about)
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There are no other versions of this object.
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Author(s) / Creator(s)Voikar, Vootele
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Other kind(s) of contributorUniversity of Helsinki
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PsychArchives acquisition timestamp2022-03-09T12:53:01Z
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Made available on2022-03-09T12:53:01Z
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Date of first publication2020-08-13
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Abstract / DescriptionProgress in pre-clinical research is built on reproducible findings, yet reproducibility has different dimensions and even meanings. Indeed, the terms reproducibility, repeatability, and replicability are often used interchangeably, although each has a distinct definition. Moreover, reproducibility can be discussed at the level of methods, analysis, results, or conclusions. Despite these differences in definitions and dimensions, the main aim for an individual research group is the ability to develop new studies and hypotheses based on firm and reliable findings from previous experiments. In practice this wish is often difficult to accomplish. In this review, issues affecting reproducibility in the field of mouse behavioral phenotyping are discussed.en
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Publication statuspublishedVersion
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Review statusnotReviewed
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CitationVoikar, V. (2020). Reproducibility of behavioral phenotypes in mouse models - a short history with critical and practical notes. Journal for Reproducibility in Neuroscience, 1, 1375. https://doi.org/10.31885/jrn.1.2020.1375
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ISSN2670-3815
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Persistent Identifierhttps://hdl.handle.net/20.500.12034/5000
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Persistent Identifierhttps://doi.org/10.23668/psycharchives.5601
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Language of contenteng
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PublisherPsychArchives
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Is version ofhttps://doi.org/10.31885/jrn.1.2020.1375
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Keyword(s)behavioral phenotypingen
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Keyword(s)mouseen
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Keyword(s)reproducibilityen
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Keyword(s)core facilityen
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Dewey Decimal Classification number(s)150
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TitleReproducibility of behavioral phenotypes in mouse models - a short history with critical and practical notesen
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DRO typearticle
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Article number1375
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Journal titleJournal for Reproducibility in Neuroscienceen
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Volume1