Orexin neuron activity in mating mice - a pilot study
Author(s) / Creator(s)
Burdakov, Denis
Karnani, Mahesh M.
Abstract / Description
Mating behaviours affect hypothalamic orexin/hypocretin neurons and vice versa. However, activity of orexin neurons has not been recorded during mating before. We report an anecdotal dataset of freely-moving miniature microscope recordings of orexin neuron activity during mating behaviours, as well as an oral sexual encounter previously undocumented in mice. Across the orexin neuron population in the male, firing rates were maximally diverse during ejaculation, similarly diverse though weaker during intromission, and inverse to this during anterior thrusting. In the female mouse, orexin neurons tended to decrease firing during intromission after a transient increase. We provide this brief dataset for re-use, to enable further studies of these rare behaviours with challenging surgical preparations.
Keyword(s)
Mating Orexin Hypocretin Calcium imaging Miniscope Freely moving recording Mouse fellatioPersistent Identifier
Date of first publication
2021-06-02
Journal title
Neuroanatomy and Behaviour
Volume
3
Article number
e17
Publisher
Episteme Health Inc.
Publication status
publishedVersion
Review status
peerReviewed
Is version of
Citation
Burdakov, D., & Karnani, M. (2021). Orexin neuron activity in mating mice - a pilot study. Neuroanatomy and Behaviour, 3, e17. http://dx.doi.org/10.23668/psycharchives.4899
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nab.2021.e17.pdfAdobe PDF - 4.83MBMD5: 25a41288f1c2d912035c0804a0b6ad43Description: Version of Record
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There are no other versions of this object.
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Author(s) / Creator(s)Burdakov, Denis
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Author(s) / Creator(s)Karnani, Mahesh M.
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PsychArchives acquisition timestamp2021-06-15T13:48:38Z
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Made available on2021-06-15T13:48:38Z
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Date of first publication2021-06-02
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Abstract / DescriptionMating behaviours affect hypothalamic orexin/hypocretin neurons and vice versa. However, activity of orexin neurons has not been recorded during mating before. We report an anecdotal dataset of freely-moving miniature microscope recordings of orexin neuron activity during mating behaviours, as well as an oral sexual encounter previously undocumented in mice. Across the orexin neuron population in the male, firing rates were maximally diverse during ejaculation, similarly diverse though weaker during intromission, and inverse to this during anterior thrusting. In the female mouse, orexin neurons tended to decrease firing during intromission after a transient increase. We provide this brief dataset for re-use, to enable further studies of these rare behaviours with challenging surgical preparations.en
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Publication statuspublishedVersionen
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Review statuspeerRevieweden
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SponsorshipThis project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement DRIVOME (grant agreement 701986). The experiments in this study were supported by the Francis Crick Institute which receives its core funding from Cancer Research UK (FC001055), the UK Medical Research Council (FC001055), and the Wellcome Trust (FC001055).en
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CitationBurdakov, D., & Karnani, M. (2021). Orexin neuron activity in mating mice - a pilot study. Neuroanatomy and Behaviour, 3, e17. http://dx.doi.org/10.23668/psycharchives.4899en
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ISSN2652-1768
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Persistent Identifierhttps://hdl.handle.net/20.500.12034/4328
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Persistent Identifierhttps://doi.org/10.23668/psycharchives.4899
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Language of contenteng
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PublisherEpisteme Health Inc.en
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Is version ofhttps://doi.org/10.35430/nab.2021.e17
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Requireshttps://doi.org/10.5281/zenodo.4813116
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Is related tohttps://doi.org/10.5281/zenodo.4820456
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Keyword(s)Matingen
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Keyword(s)Orexinen
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Keyword(s)Hypocretinen
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Keyword(s)Calcium imagingen
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Keyword(s)Miniscopeen
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Keyword(s)Freely moving recordingen
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Keyword(s)Mouse fellatioen
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Dewey Decimal Classification number(s)150
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TitleOrexin neuron activity in mating mice - a pilot studyen
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DRO typearticleen
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Article numbere17
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Journal titleNeuroanatomy and Behaviouren
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Volume3
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Visible tag(s)Version of Record